14-12-2025
جامعة الملك عبدالعزيز
KING ABDULAZIZ UNIVERSITY
Faculty of Dentistry
Document Details
Document Type
:
Article In Journal
Document Title
:
Bisphosphonate effects upon relapse of orthodontically moved teeth
تأثير مادة البيسفوسفونات على الحركة الإرتدادية للأسنان المعالجة بالتقويم عند الفئران
Document Language
:
English
Abstract
:
This study was designed to identify the effects of bisphosphonate (BP) administration on structure and functions of osteoclasts in alveolar bone resorption during relapse after orthodontic movement of rat molars.Twenty four male rats were used in this study.ToProduce orthodontic force,elastic band was inserted between the upper first and second molars for 21 days. at one day befor elastic band removal, bisphosphonate was administered intraperitoneally. After elastic band removal, the rats were further maintained fpr 0.5 and 10 days. the distal relaose movement of the first molars was examined by means of light, scanning and transmission electron microscopy.In disphosphonate-administred rate, there was adecrease in the distal relapse movement in comparison to the control group and the histological observations revealed reduction in osteoclasts aggregation along the alveolar bone sufaces opposite the pressure side of the periodontal ligament with degenerative structural changes especially at the fifth day. it was concluded that relaps in experimentally moved rat molars through a mechanism involving impairment of the structure and resorptive functions of osteoclasts.
ISSN
:
0
Journal Name
:
Egyptian Orthodontic Journal
Volume
:
29
Issue Number
:
1
Publishing Year
:
2006 AH
2006 AD
Article Type
:
Article
Added Date
:
Monday, May 5, 2008
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
أحمد عفيفي
afifi, Ahmed
Researcher
Doctorate
aafifi@kau.edu.sa
هشام عثمان
Othman, Hisham
Investigator
Doctorate
hothman@kau.edu.sa
Files
File Name
Type
Description
Bisphosphonate Effect.pdf
pdf
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