10-12-2025
جامعة الملك عبدالعزيز
KING ABDULAZIZ UNIVERSITY
Faculty of Medicine
Document Details
Document Type
:
Article In Journal
Document Title
:
Assessment of Heart Rate Variability as an index of Cardiac autonomic modulation in Controlled and Depressed persons
Assessment of Heart Rate Variability as an index of Cardiac autonomic modulation in Controlled and Depressed persons
Document Language
:
English
Abstract
:
Background: Under steady state conditions, heart rate displays spontaneous beat-to-beat fluctuation. This fluctuation results from the continuous interaction between the neural or humoral control of cardiovascular function. The fluctuation of heart rate around its mean is called heart rate variability (HRV). The mechanisms underlying the relationship between depression and cardiac events remain unclear. A disturbance of cardiac Sympathovagal balance is one of the most plausible candidates in depressed patients. Aim: To evaluate cardiac Sympathovagal activity in depressed, non cardiac patients. Study design: A 24-hour Holter electrocardiogram (ECG) was recorded in15 newly diagnosed depressed patients and 15 healthy age and sex matched control subjects. Sympathovagal balance was evaluated through time domain parameters of Heart rate variability (HRV). Results: 15th patients with depression disorders were found to have elevated resting heart rate (HR), low heart rate variability (HRV); decreased Mean NNI, SDNN, rMSSD and pNN50. Conclusion: There is considerable evidence of cardiac autonomic dysregulation In depressed patients, measured by HRV parameters and these abnormalities may explain the increased cardiac morbidity and mortality rates in these patients.
ISSN
:
0749-8063
Journal Name
:
Benha medical journal
Volume
:
25
Issue Number
:
1
Publishing Year
:
2008 AH
2008 AD
Article Type
:
Article
Added Date
:
Wednesday, March 17, 2010
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
خالد عظام
ezam, khaled
Researcher
Doctorate
Files
File Name
Type
Description
26017.doc
doc
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