17-12-2025
جامعة الملك عبدالعزيز
KING ABDULAZIZ UNIVERSITY
Faculty of Environmental Sciences
Document Details
Document Type
:
Article In Journal
Document Title
:
Neuroimunotoxic Effects of occupation Exposure to Lead and Mercury
التأثيرات العصبية المناعية السامة للتعرض المهني لكل من الرصاص والزئبق
Document Language
:
English
Abstract
:
Occupational exposure to lead and mercury continues to pose a threat to workers, making early detection of their neurotoxic effects a pressing concern. The levels of sera autoantibodies to nervous system proteins can be of good value in this purpose. This study was carried out to detect subclinical neurotoxicity caused by occupational exposure to lead (n = 27) and mercury (n = 24) using blood levels autoantibodies against neural proteins. The autoantibodies used were the IgG and IgM types of anti-NF68, anti- NF160, anti-NF200, anti-MBP and anti-GFAP. Compared to the controls (n = 30), both exposed groups showed higher percentage of positive titers for anti-NF68 (IgG), anti-NF200 (IgM), anti-GFAP (IgG, IgM) and anti-MBP (IgM). Higher median values were obtained for anti-NF200 (IgG, IgM), anti-GFAP (IgM) and anti-MBP (IgM). Anti-NF160 was not affected by exposure. Determination of sera neuroantibodies levels is recommended in the biological monitoring of lead and mercury exposure.
ISSN
:
1319-1039
Journal Name
:
Meteorology, Environment and Arid Land Agriculture Sciences Journal
Volume
:
18
Issue Number
:
1
Publishing Year
:
1428 AH
2007 AD
Article Type
:
Article
Added Date
:
Monday, August 6, 2012
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
مجدي يوسف شامي
Shamy, Mjde Y.
Investigator
Doctorate
Files
File Name
Type
Description
34071.pdf
pdf
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