14-12-2025
جامعة الملك عبدالعزيز
KING ABDULAZIZ UNIVERSITY
Center of Excellence In Genomic Medicine Research
Document Details
Document Type
:
Article In Journal
Document Title
:
The need for predictive, prognostic, objective and complementary blood-based biomarkers in osteoarthritis (OA)
The need for predictive, prognostic, objective and complementary blood-based biomarkers in osteoarthritis (OA)
Document Language
:
English
Abstract
:
Osteoarthritis (OA) has traditionally been viewed as a noninflammatory arthropathy and has not been considered a ‘serious disease’. However, this view has radically changed in recent years, due to the complexity and heterogeneity of the patient populations, spiralling socio-economical costs and long-term impact on the quality of life of affected individuals. There is an acute need for objective and non-invasive diagnostic biomarkers in OA, markers that can stratify patient subtypes and thereby direct therapeutic treatments at an earlier disease stage (read personal health care (PHC)) (Conaghan, 2013). Increased interest in the development of new diagnostic and prognostic tests for early forms of OA may incorporate the use of blood-based biomarkers; however, both research and regulated development and approval are still needed to reach a diagnostically important significant point where a given biomarker will benefit the clinical management of the patient.
ISSN
:
2352-3964
Journal Name
:
EBioMedicine
Volume
:
7
Issue Number
:
1
Publishing Year
:
1437 AH
2016 AD
Article Type
:
Article
Added Date
:
Wednesday, July 12, 2017
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
Anne-C. Bay-Jensen
Bay-Jensen, Anne-C.
Researcher
Doctorate
Yves Henrotin
v, Yves
Researcher
Doctorate
Morten Karsdal
Karsdal, Morten
Researcher
Doctorate
Ali Mobasheri
Mobasheri, Ali
Researcher
Doctorate
Files
File Name
Type
Description
41975.pdf
pdf
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